Oral: Initial: Gout Flare: 1.2 milligrams by mouth at the very first indication of the flare followed by 0.6 milligrams one hr later on. Maximum: Gout Flare: 1.8 milligrams orally over a one hr duration Coadministration with solid CYP450 3A4 preventions: 0.6 mg by mouth followed by 0.3 mg one hour later on. Dose to be repeated no earlier than 3 days. Coadministration with moderate CYP450 3A4 preventions: 1.2 milligrams orally for one dosage simply. Dose to be repeated no earlier than 3 days. Coadministration with P-glycoprotein preventions: 0.6 milligrams orally for one dosage only. Dosage to be duplicated no earlier compared to 3 days.
(Unlabeled use): Oral: 0.5 to 0.6 milligrams by mouth once daily for 3 to 4 days a week (much less than 1 attack/year). 0.5 to 0.6 milligrams by mouth daily (higher than 1 attack/year). Intense situations might need 1 to 1.8 mg/day.
(Unlabeled use): Initial: 0.6 to 1.2 milligrams by mouth daily every day for the first 1 to 2 weeks. Maintenance: 0.6 to 1.2 mg by mouth daily 1 to 2 times every week is typically made use of to stop reoccurrence of fibromatosis.
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